ZuriTIAM 100
Tiamulin 10%
Pleuromutilin antibiotic rapidly absorbed from the gut for the treatment of Mycoplasma infections and respiratory disease.
About ZuriTIAM 100
ZuriTIAM 100 delivers tiamulin hydrogen fumarate at 100 g per kg, a semi-synthetic pleuromutilin antibiotic with outstanding activity against Mycoplasma. Tiamulin's unique tricyclic diterpene structure provides a mode of action completely distinct from all other antibiotic classes.
Why choose ZuriTIAM 100
Unique Pleuromutilin Class
Completely distinct chemical class from all other antibiotics — no cross-resistance with macrolides or tetracyclines.
Mycoplasma Excellence
Tiamulin is among the most potent antibiotics available against Mycoplasma gallisepticum and M. synoviae.
Rapid Absorption
Rapidly and completely absorbed from the gut following in-feed delivery.
Respiratory Tissue Distribution
High tissue-to-plasma ratios in lung and respiratory mucosa.
Resistance Reserve
The unique binding site means tiamulin remains effective against strains resistant to other classes.
CRD and Complex Respiratory
Effective for treatment and control of CRD caused by Mycoplasma.
How ZuriTIAM 100 works
Unique 50S Binding Site
Tiamulin binds to the 50S ribosomal subunit at domain V of 23S rRNA — a locus distinct from macrolides.
Translocation Block
Binding prevents EF-G-mediated translocation of peptidyl-tRNA, arresting protein synthesis.
Rapid Systemic Distribution
After oral absorption, tiamulin distributes rapidly into lung and respiratory mucosa.
Mycoplasma Elimination
High tissue distribution and very low Mycoplasma MICs allow bactericidal concentrations at standard doses.
Recommended dosage & use
Always follow veterinary guidance. The dosages below are standard recommendations; higher doses may be advised during disease challenges or deficiency conditions.
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